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What works, and what does not

Black cohosh

The most bought herb for menopause. Cochrane found the evidence insufficient, and there are liver injury reports.

For hot flashes and night sweats: not provenFor use if you have liver problems: avoid

The short answer

For hot flashes and night sweats: not proven
A Cochrane review of 16 studies in 2,027 women found insufficient evidence to support using it. NICE says there is some evidence, with uncertain safety.
For use if you have liver problems: avoid
At least 83 cases of liver damage worldwide have been linked with black cohosh, including hepatitis and liver failure.

What it is

A plant native to North America, also called Actaea racemosa. It was used by Native Americans for period problems, and it is now the most purchased herbal product for menopause symptoms. How it works is not known.

What the studies say

  • A Cochrane review of 16 studies in 2,027 women found insufficient evidence to support black cohosh for menopausal symptoms, and called for better trials.
  • NICE says people can be told there is some evidence that black cohosh may relieve hot flashes and night sweats. It also says preparations vary, their safety is uncertain, and interactions with other medicines have been reported.
  • The Menopause Society reviewed the evidence in 2023 and lists supplements and herbal remedies, black cohosh included, among the things it does not recommend for hot flashes.
  • The NHS says there is very little evidence on how well herbal remedies like black cohosh work, or how safe they are.
  • Most trials ran for 6 months or less, so nobody has tested what happens over years.

How much people take in trials

One widely studied product is standardised to the equivalent of 40mg of black cohosh root and rhizome per daily dose. Products differ from each other, so one product's dose does not read across to another.

This is what the research used. It is not a dose for you.

What a label is allowed to say

For menopause symptoms, black cohosh is treated as a medicine in the UK. A product sold for that use needs a traditional herbal registration, shown by the THR mark. A food supplement cannot make that claim.

In the US the rules are looser. A label may say how a nutrient supports the body if the company holds evidence for it. The FDA does not check the claim first, which is why US labels carry the line saying the FDA has not evaluated it.

Safety

  • At least 83 cases of liver damage have been reported worldwide in people using black cohosh, including hepatitis, liver failure and raised liver enzymes.
  • Stop and get medical help if you notice yellowing skin or eyes, dark urine, unusual tiredness or pain in the upper right of your abdomen.
  • Herbal products are not regulated like medicines. What is in the bottle can differ from what is on the label.
  • Interactions with other medicines have been reported, so a pharmacist should see your full list first.

Ask your doctor first if

  • You have liver disease, or take medicines that affect the liver.
  • You have had breast cancer or are at high risk of it.
  • You take any prescription medicine at all.

This is general information, not medical advice. Check with your doctor or pharmacist, especially if you take medication.

Sources

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