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Also known as: Dehydroepiandrosterone, Prasterone, Intrarosa
A precursor hormone produced naturally by the adrenal glands. Available as an oral supplement or vaginal pessary (Intrarosa, licensed for vaginal atrophy). Used to support oestrogen and testosterone levels, particularly in women with adrenal insufficiency or premature ovarian insufficiency.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your GP or specialist before starting, stopping, or changing any intervention.
Regulatory status does not mean an intervention is safe or unsafe. Laws vary by country — check your local regulations.
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Research context compiled from published sources
Converted peripherally to oestrogens and androgens in target tissues. Vaginal DHEA (prasterone) acts locally in vaginal cells to produce oestradiol and testosterone, restoring vaginal epithelial health without significant systemic hormone elevation.
Moderate Research
Some human clinical trials exist, but the evidence base is still developing.
Unknown
Dose ranges from published research. Individual dosing should be determined with your healthcare provider based on your specific circumstances.
Factual research context from published sources — not a safety assessment or recommendation. Research classifications may change as new data emerges.
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Data last updated: No data yet