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Supplement

Evening Primrose Oil

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Also known as: EPO, Oenothera biennis, GLA supplement

An oil extracted from the seeds of the evening primrose plant, rich in gamma-linolenic acid (GLA). Traditionally used for breast pain (mastalgia), PMS, and menopausal hot flushes. Evidence for hot flush reduction is modest. Also used for skin health and inflammation.

This page contains self-reported experiences from the Narrated community โ€” not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.

Regulatory status is factual context, not a clinical-risk assessment. Laws vary by country.

Community Experiences

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Research Context

Research context compiled from published sources

How does Evening Primrose Oil work?

GLA is a precursor to anti-inflammatory prostaglandins (PGE1). Modulates inflammatory pathways and may influence prostaglandin balance in ways that affect cyclical breast pain and skin barrier function. Proposed effects on vasomotor symptoms may relate to prostaglandin-mediated thermoregulation.

Research Depth

Unknown

Long-Term Evidence

Limited

Only short-term data available. Long-term effects are not well understood.

Known Interactions
Anticoagulants (may increase bleeding risk)Antiplatelet drugsPhenothiazines (may lower seizure threshold)
Reported Contraindicated Populations
Epilepsy (may lower seizure threshold)Bleeding disordersPregnancy (use with caution)
Published Dose Ranges
2โ€“4 g/dayoral ยท once or twice daily with food
Product labels/clinical trials

Dose ranges from published research. Individual dosing is context-specific and belongs in a healthcare conversation.

Factual research context from published sources โ€” not a clinical-risk assessment or guidance. Research classifications may change as new data emerges.

Related Approaches

Other Supplement tracked on Narrated.

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Evening Primrose Oil โ€” What Women Report | Narrated