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Also known as: Diindolylmethane, 3,3'-Diindolylmethane
A compound derived from the digestion of indole-3-carbinol, found naturally in cruciferous vegetables such as broccoli and cabbage. Used to support oestrogen metabolism, particularly to promote conversion to less potent oestrogen metabolites. Popular for PMS, hormonal acne, and oestrogen dominance.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.
Total Reports
14
Median Score (Wk 8)
6/10
Would Continue
71%
Avg Duration
11 wk
Most Common Goal
skin hair
Most Reported Side Effect
Dark urine (harmless) (43%)
Based on self-reported community data. Scores use a 1–10 scale.
Regulatory status does not mean an approach is safe or unsafe. Laws vary by country — check your local regulations.
Women who reported on DIM mentioned using it for the following goals. This does not mean it is intended for or achieves any of these outcomes.
Aggregated patterns from 14 self-reported experiences with DIM.
71% of women said they would continue this protocol
5.8/10 average self-reported outcome score at week 8
Most commonly reported effects: Dark urine (harmless), Gas and bloating, Headache
Outcome Score Distribution (Week 8)
14 of 14 reports included a week 8 score
Would Continue Protocol
14 of 14 reports included this response
Reported Goals
Commonly Reported Effects
Percentage of reports mentioning each effect
Based on 14 self-reported experiences. This is community data, not clinical evidence. Individual outcomes vary. Discuss any intervention with your healthcare provider.
14 reports from women who tried DIM
I gave DIM a fair trial for my adult-onset acne. Some improvement in sleep got better but the weight didn't shift persisted. It might work for others but was modest for me.
Unfortunately DIM didn't work for my sudden hair thinning. I gave it 8 weeks and the symptoms persisted despite consistent use. Disappointing but at least I know now.
I was sceptical about DIM but desperate with my thinning hair and dry skin. Slow start honestly. By week 8, I felt significantly better. It's been a real game-changer for me.
DIM helped somewhat with my hair loss and brittle nails — mood stabilised slightly, though sleep didn't improve much. It's OK but I expected more.
I've been using DIM for about 8 weeks now for sudden hair thinning. I noticed a subtle improvement around week 3. I felt like I had my life back. Best decision I made for my health.
Research context compiled from published sources
Modulates oestrogen metabolism by promoting the 2-hydroxylation pathway (producing less active 2-hydroxyoestrone) rather than the 16α-hydroxylation pathway. Also influences CYP1A2 enzyme activity and may have anti-oestrogenic effects in oestrogen-dominant tissues. Some evidence for anti-proliferative effects in cell studies.
Emerging Research
Limited human trials. Most evidence comes from animal studies or small human studies.
Limited
Only short-term data available. Long-term effects are not well understood.
Dose ranges from published research. Individual dosing should be determined with your healthcare provider based on your specific circumstances.
Factual research context from published sources — not a safety assessment or recommendation. Research classifications may change as new data emerges.
Other Supplement tracked on Narrated.
Data last updated: March 27, 2026