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Also known as: Crocus sativus, Affron, saffron supplement
A standardised extract from the stigma of Crocus sativus. Used for mood support, with several RCTs showing benefit for mild to moderate depression comparable to some SSRIs. Also studied for PMS, appetite control, and libido. Relevant to perimenopausal women experiencing mood fluctuations.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.
Total Reports
15
Median Score (Wk 8)
6/10
Would Continue
73%
Avg Duration
12 wk
Most Common Goal
perimenopause
Most Reported Side Effect
Dizziness (47%)
Based on self-reported community data. Scores use a 1–10 scale.
Regulatory status does not mean an approach is safe or unsafe. Laws vary by country — check your local regulations.
Women who reported on Saffron Extract mentioned using it for the following goals. This does not mean it is intended for or achieves any of these outcomes.
Aggregated patterns from 15 self-reported experiences with Saffron Extract.
73% of women said they would continue this protocol
6.1/10 average self-reported outcome score at week 8
Most commonly reported effects: Dizziness, Dry mouth, Appetite changes
Outcome Score Distribution (Week 8)
15 of 15 reports included a week 8 score
Would Continue Protocol
15 of 15 reports included this response
Reported Goals
Commonly Reported Effects
Percentage of reports mentioning each effect
Based on 15 self-reported experiences. This is community data, not clinical evidence. Individual outcomes vary. Discuss any intervention with your healthcare provider.
15 reports from women who tried Saffron Extract
Saffron Extract helped somewhat with my mood swings and rage episodes — mood stabilised slightly, though my mood was still up and down. It's OK but I expected more.
After 10 weeks on Saffron Extract, I'd say it made a modest difference to my sleep disruption and joint pain. Some symptoms improved while others stayed the same. It might work for others but was modest for me.
Saffron Extract has been really helpful for my mood swings and rage episodes. I noticed I had more energy fairly quickly. I was sleeping through the night over the following weeks. Still taking it and plan to continue.
Started Saffron Extract alongside mood swings and rage episodes management. Week 3: I felt a bit more like myself. Week 8: I felt significantly better. Still taking it and plan to continue.
I started Saffron Extract after dealing with irregular periods and mood swings for months. By week 2 I noticed I felt a bit more like myself. At 12 weeks, I was sleeping through the night. I'm glad I tried it.
Research context compiled from published sources
Active constituents (crocin, safranal, picrocrocin) modulate serotonin metabolism by inhibiting serotonin reuptake in synapses. Also has NMDA receptor antagonist properties and anti-inflammatory effects. May modulate the HPA axis, reducing cortisol secretion.
Unknown
Limited
Only short-term data available. Long-term effects are not well understood.
Dose ranges from published research. Individual dosing should be determined with your healthcare provider based on your specific circumstances.
Factual research context from published sources — not a safety assessment or recommendation. Research classifications may change as new data emerges.
Other approaches tracked on Narrated.
Data last updated: March 27, 2026