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hormone

DHEA

Also known as: Dehydroepiandrosterone, Prasterone, Intrarosa

A precursor hormone produced naturally by the adrenal glands. Available as an oral supplement or vaginal pessary (Intrarosa, licensed for vaginal atrophy). Used to support oestrogen and testosterone levels, particularly in women with adrenal insufficiency or premature ovarian insufficiency.

This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.

Regulatory status does not mean an approach is safe or unsafe. Laws vary by country — check your local regulations.

Community Experiences

0 reports from women who tried DHEA

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Research Context

Research context compiled from published sources

How does DHEA work?

Converted peripherally to oestrogens and androgens in target tissues. Vaginal DHEA (prasterone) acts locally in vaginal cells to produce oestradiol and testosterone, restoring vaginal epithelial health without significant systemic hormone elevation.

Research Depth

Moderate Research

Some human clinical trials exist, but the evidence base is still developing.

Long-Term Evidence

Unknown

Known Interactions
AnticoagulantsInsulin/antidiabeticsCorticosteroids
Reported Contraindicated Populations
History of hormone-sensitive cancers (caution)PregnancyPCOS (potential androgen excess)
Published Dose Ranges
6.56.5 mg/dayvaginal pessary · once daily at bedtime
BNF
2550 mg/dayoral · once daily
BMS

Dose ranges from published research. Individual dosing should be determined with your healthcare provider based on your specific circumstances.

Factual research context from published sources — not a safety assessment or recommendation. Research classifications may change as new data emerges.

Related Approaches

Other approaches tracked on Narrated.

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