Micronized Progesterone
Also known as: Utrogestan, Prometrium
Body-identical progesterone derived from plant sources and micronized for absorption. Used to protect the uterine lining in women taking oestrogen HRT. Can be taken orally or vaginally and is associated with better sleep and fewer side effects than synthetic progestogens.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.
Regulatory status is factual context, not a clinical-risk assessment. Laws vary by country.
Community Experiences
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Research Context
Research context compiled from published sources
How does Micronized Progesterone work?
Binds to progesterone receptors in the endometrium, preventing oestrogen-driven hyperplasia. Micronization increases bioavailability. Metabolites (allopregnanolone) act on GABA receptors, contributing to its sedative and anxiolytic properties.
Research Depth
Well Studied
Extensive human research over many years, including randomized controlled trials.
Long-Term Evidence
Well Characterized
Decades of long-term human-use data are available.
Known Interactions
Reported Contraindicated Populations
Published Dose Ranges
Dose ranges from published research. Individual dosing is context-specific and belongs in a healthcare conversation.
Factual research context from published sources — not a clinical-risk assessment or guidance. Research classifications may change as new data emerges.
Related Approaches
Other approaches tracked on Narrated.
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