Dydrogesterone
Also known as: Femoston progestogen, Duphaston
A synthetic progestogen used as the progestogen component in Femoston combined HRT. Structurally similar to natural progesterone and considered to have a more favourable side-effect profile than older synthetic progestogens. Does not have androgenic activity.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.
Regulatory status is factual context, not a clinical-risk assessment. Laws vary by country.
Community Experiences
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Research Context
Research context compiled from published sources
How does Dydrogesterone work?
Binds selectively to progesterone receptors with high affinity, protecting the endometrium from oestrogen-induced hyperplasia. Unlike norethisterone, it lacks androgenic or oestrogenic activity, which may reduce some common progestogen side effects such as acne and mood changes.
Research Depth
Well Studied
Extensive human research over many years, including randomized controlled trials.
Long-Term Evidence
Well Characterized
Decades of long-term human-use data are available.
Known Interactions
Reported Contraindicated Populations
Published Dose Ranges
Dose ranges from published research. Individual dosing is context-specific and belongs in a healthcare conversation.
Factual research context from published sources — not a clinical-risk assessment or guidance. Research classifications may change as new data emerges.
Related Approaches
Other approaches tracked on Narrated.
Data last updated: No data yet