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Supplement

Iodine

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Also known as: potassium iodide, iodine supplement, Lugol's solution

An essential trace element required for thyroid hormone synthesis. The UK RNI is 140mcg/day. Iodine deficiency can impair thyroid function and is common in some UK populations, particularly those who do not consume dairy or fish. However, excess iodine can worsen autoimmune thyroid conditions including Hashimoto's thyroiditis.

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Regulatory status is factual context, not a clinical-risk assessment. Laws vary by country.

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Research Context

Research context compiled from published sources

How does Iodine work?

Iodine is incorporated into thyroglobulin in the thyroid gland and used to synthesise thyroxine (T4) and triiodothyronine (T3) via thyroid peroxidase. Without adequate iodine, the thyroid cannot produce sufficient hormones, leading to hypothyroidism. Excessive iodine can paradoxically inhibit thyroid hormone synthesis (Wolff-Chaikoff effect) and exacerbate autoimmune thyroiditis.

Research Depth

Well Studied

Extensive human research over many years, including randomized controlled trials.

Long-Term Evidence

Well Characterized

Decades of long-term human-use data are available.

Known Interactions
Levothyroxine (excess iodine may alter thyroid hormone levels)Antithyroid drugs (antagonistic interaction)Lithium (additive hypothyroid effect)
Reported Contraindicated Populations
Hashimoto's thyroiditis (excess iodine may worsen autoimmune flares)Graves' diseaseIodine allergy (rare true allergy vs contrast media reactions)
Published Dose Ranges
140250 mcg/dayoral · once daily
NHS/WHO

Dose ranges from published research. Individual dosing is context-specific and belongs in a healthcare conversation.

Factual research context from published sources — not a clinical-risk assessment or guidance. Research classifications may change as new data emerges.

Related Approaches

Other Supplement tracked on Narrated.

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