Phosphatidylserine
Also known as: PS, phosphatidylserine supplement
A phospholipid found in high concentrations in brain cell membranes. Used for cognitive support, cortisol modulation, and stress resilience. Some evidence for blunting the cortisol response to exercise and psychological stress. Used by perimenopausal women for brain fog and HPA axis support.
This page contains self-reported experiences from the Narrated community — not clinical data. Outcomes are subjective. Always consult your doctor or specialist before starting, stopping, or changing any approach.
Regulatory status is factual context, not a clinical-risk assessment. Laws vary by country.
Community Experiences
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Research Context
Research context compiled from published sources
How does Phosphatidylserine work?
Integral component of neuronal cell membranes, supporting membrane fluidity, receptor function, and neurotransmitter release. Supplementation may attenuate the HPA axis cortisol response to stress by modulating ACTH signalling. Also supports acetylcholine production and mitochondrial function in neurons.
Research Depth
Unknown
Long-Term Evidence
Limited
Only short-term data available. Long-term effects are not well understood.
Known Interactions
Reported Contraindicated Populations
Published Dose Ranges
Dose ranges from published research. Individual dosing is context-specific and belongs in a healthcare conversation.
Factual research context from published sources — not a clinical-risk assessment or guidance. Research classifications may change as new data emerges.
Related Approaches
Other Supplement tracked on Narrated.
Data last updated: No data yet